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Genomic and epigenetic alterations with relevant molecular profiling have been cataloged for patient-derived xenograft lines in the Mayo Clinic Brain Tumor Patient-Derived Xenograft National Resource.
Multi-omic data available on the lines from the Mayo Clinic PDX National Resource have been uploaded into cBioPortal, enabling users to readily query all the multi-omic data at the gene level.
RNA sequencing was performed on a single biological sample for each patient-derived xenograft model in the PDX National Resource. Details about which platform was used for each individual glioblastoma line are available.
Whole-exome sequencing (WES) was performed on tumor tissue from a single biological sample for each patient-derived xenograft model in the PDX National Resource.
Methylation array analysis was performed on tumor tissue from a single biological sample for each patient-derived xenograft model in the PDX National Resource.
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