About the Lab

The Translational Neuro-Oncology Laboratory of Jann N. Sarkaria, M.D., at Mayo Clinic is focused on developing novel therapeutic strategies for people with glioblastoma multiforme and brain metastases.

Global research interests in the lab include:

  • Understanding the basis of resistance to chemotherapy and radiation
  • Identifying methods to overcome therapy resistance
  • Integration of novel signal transduction inhibitors into conventional therapies for newly diagnosed or recurrent glioblastoma multiforme
  • Use of next-generation sequencing and proteomics to guide individualized therapy for patients with glioblastoma multiforme