Overview

The Tendon and Soft Tissue Biology Laboratory of Peter C. Amadio, M.D., at Mayo Clinic

The Tendon and Soft Tissue Biology Laboratory of Peter C. Amadio, M.D., at Mayo Clinic focuses its research on injuries to tendons and soft tissues.

Flexor tendon injury and repair poses a surgical challenge because of the high complication rate, including adhesion formation, gapping and rupture, which typically require a second surgery to restore the finger function.

The research goals of the Tendon and Soft Tissue Biology Lab have focused on several important aspects related to improving the outcomes of flexor tendon repair. These include lubricant effect, optimal postoperative rehabilitation, appropriate surgical repair and reconstruction techniques, and role of growth factor on tendon healing and adhesion formation.

Current research topics within the Tendon and Soft Tissue Biology Lab relate to a wide range of disciplines and technologies, such as orthopedics, biomechanics, biochemistry, and molecular and cell biology.