High-Resolution Computerized Tomography (CT) and Cardiovascular Disease

High-Resolution Computerized Tomography (CT) and Cardiovascular Disease

For years, cardiovascular disease has been the No. 1 cause of death in the United States, and Mayo Clinic researchers predict an increasing incidence of heart disease and related deaths in the future. For this reason, research to develop and assess new diagnostic techniques and therapies for fighting cardiovascular disease is a health care priority.

This research project works with applied high-resolution computerized tomography (CT) methods to detect and explore the effects of major risk factors for cardiovascular disease, such as hypertension and hypercholesterolemia on the myocardial and renal microvessels. With advanced medical imaging techniques, researchers are able to identify the structural and functional changes of microcirculation in the heart and kidney, in order to develop and evaluate new approaches to these pathogenic conditions. These studies are likely to shed important light on the mechanisms of atherosclerotic heart and kidney disease and suggest new preventive and interventional measures.

Furthermore, the lab has developed a novel imaging technique with high-resolution micro-CT, which can identify early changes in the cardiac and renal vascular structure. In addition, the lab has a current project that focuses on the endothelial progenitor cell transplantation in atherosclerotic renal artery disease. The future direction of this research is looking for better candidates for the cell therapy of cardiovascular diseases.

For more information contact: zhu.xiangyang@mayo.edu