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Glial cells, including astrocytes (red) and oligodendrocytes (green), play key roles in regulating brain function and its response to injury. Dr. Scarisbrick's lab studies how astrocyte and oligodendrocyte metabolic activities are altered in CNS injury and disease and how this impacts nerve function. With this knowledge, Dr. Scarisbrick's team is developing new pharmacologic, cellular and rehabilitation interventions to modulate function of these cells to promote neural plasticity and repair.
"Harnessing the dynamic action of proteases holds great promise for the treatment of neurological injury and disease"
Dr. Scarisbrick's Neuroregeneration and Neurorehabilitation Laboratory at Mayo Clinic is focused on neural repair and regeneration. The lab is working to solve fundamental mysteries of biology and physiology that will inform mechanisms and new targets for therapy.
Current projects use genetic and pharmacotherapy approaches as a starting point to understand pathological mechanisms and develop new therapies for individualized precision regenerative medicine.
Dr. Scarisbrick and her colleagues have published a variety of research findings on neural repair and neural regeneration.
Contact Dr. Scarisbrick's Neuroregeneration and Neurorehabilitation Laboratory at Mayo Clinic about research, collaboration or educational opportunities.
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