About the Lab

The Mayo Clinic Neurogenesis and Brain Tumors Laboratory, under the direction of Hugo Guerrero Cazares, M.D., Ph.D., focuses on understanding the interaction of the human neurogenic niche and brain tumors. Specifically, Dr. Guerrero Cazares' research team conducts in vitro, in vivo and ex vivo studies on glioblastoma multiforme — the most common, aggressive and proliferative primary brain tumor in adults — and on the migration of neural progenitor cells in people.

Areas of interest

Specific areas of interest in the Neurogenesis and Brain Tumors Laboratory include:

  • Understanding the role of cerebrospinal fluid on the invasiveness of brain tumor cells
  • Studying the potential malignant transformation of human neural progenitor cells in proximity with brain tumors
  • Studying the invasion of healthy brain by tumor cells ex vivo