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The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation
Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency
Neuropathological examination of sense and antisense RNA foci and c9RAN protein pathology in c9FTD/ALS
Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments
Structure/function analysis of TDP-43 neurotoxicity in C. elegans
Wild-type human TDP-43 expression causes TDP-43 phosphorylation, motor deficits, early mortality, and mitochondrial aggregation in transgenic mice
CHIP facilitates the degradation of aberrant PHF-tau species by regulating the Hsp90/chaperone complex
CHIP failitates the aggregation of toxic phophorylated tau species
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