Publications

See a list of Dr. Bu's publications on PubMed

Recent key publications

Liu CC, Zhao N, Yamaguchi Y, Cirrito JR, Kanekiyo T, Holtzman DM, Bu G. Neuronal heparin sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease. Science Translational Medicine. 2016;8:332ra44.

Shinohara M, Kanekiyo T, Yang L, Linthicum D, Shinohara M, Fu Y, Price L, Frisch-Daiello JL, Han X, Fryer JD, Bu G. APOE2 eases cognitive decline during aging: Clinical and preclinical evaluations. Annals of Neurology. 2016;79:758.

Liu CC, Hu J, Tsai CW, Yue M, Melrose HL, Kanekiyo T, Bu G. Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain. The Journal of Neuroscience. 2015;35:5851.

Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G. Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease. Neuron. 2014;84:63.

Kanekiyo T, Xu H, Bu G. ApoE and Aβ in Alzheimer's disease: Accidental encounters or partners? Neuron. 2014;81:740.

Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G. Neuronal clearance of amyloid-β by endocytic receptor LRP1. The Journal of Neuroscience. 2013;33:19276.

Liu CC, Kanekiyo T, Xu H, Bu G. Apolipoprotein E and Alzheimer's disease: Risk, mechanisms, and therapy. Nature Reviews Neurology. 2013;9:106.