Human Studies

The Neural Engineering Laboratory's Human Studies Team seeks to improve the efficacy of deep brain stimulation in patients by studying the role of stimulation-induced neurochemical changes in patients with movement disorders or psychiatric conditions. The team conducts acute neurochemical recordings in patients undergoing DBS lead implantation using the Wireless Instantaneous Neurotransmitter Concentration Sensing System (WINCS) and Harmoni devices developed in the Neural Engineering Laboratory.

Meet the team

  • Paul H. Min, Ph.D.
    • Project Leader
    • Dr. Min is a biomedical engineer with a background in neuroimaging and advanced imaging techniques, including 7-tesla MRI, high-resolution positron emission tomography (PET) and ultrahigh field functional MRI (fMRI). His group conducts research on the mechanism of action in deep brain stimulation by using simultaneous fMRI and electrochemistry measures.
  • Stephan J. Goerss
    • Stephan Goerss has a background in the field of stereotactic and image-guided neurosurgery. He joined the Mayo Clinic Department of Neurologic Surgery in 1984 as part of a team to establish the department as a center for stereotactic development. His work there furthered the mechanical design of the Compass stereotactic system. Stephan also oversaw the image-guided surgery practice for the departments of Neurologic Surgery and Orthopedic surgery.

      Stephen is now a contractor with the Neural Engineering Lab. His interest is in developing instruments and devices to enhance the use of imaging and technology in surgery.

  • Cynthia (Cindy) J. Stoppel, CCRP
    • Clinical Research Coordinator
    • Cindy Stoppel is a certified clinical research coordinator with 25 years of experience at Mayo Clinic and more than 14 years coordinating studies in neurology, epidemiology and psychiatry. She came to the Neural Engineering Lab in 2015 to work on human trials with deep brain stimulation.
  • Jan T. Hachmann, M.D.
    • Research Fellow
    • Dr. Hachmann earned his medical degree from Ruprecht-Karls-University Heidelberg in Germany in 2016. He is also awaiting a master's degree in translational medical research. His research background is in molecular oncology, spinal cord injury, spinal cord stimulation for neurorestoration and neuromodulation therapies.

      After a previous appointment with the Neural Engineering Lab's Spinal Cord Injury Team in 2012-2013, Dr. Hachmann completed his medical education and rejoined the laboratory as a postdoctoral fellow on the Human Studies Team. His goal is to help improve understanding of the mechanisms of deep brain stimulation and advance translational efforts of advanced neuromodulation therapies toward the clinical setting.

  • Eugene S. Bah
    • M.D./Ph.D. Student
    • Eugene Bah earned a Bachelor’s of Science degree in chemistry from Worcester State University in 2012. He conducted structural biology research with Dr. Andrei Korostelev at the University of Massachusetts Medical School and then joined the M.D./Ph.D. program at Mayo Clinic in 2014. He is now working on his doctorate in the Neural Engineering Laboratory after finishing his first two years of medical school.