Funding

The Multiple Sclerosis Laboratory of Moses Rodriguez, M.D., has received numerous grants to support multiple sclerosis research, including funding from the National Institutes of Health, the Department of Defense, the National Multiple Sclerosis Society and many others.

Investigator & Role Grant Title Funding Source Duration
Isobel A. Scarisbrick, Ph.D., principal investigator; Moses Rodriguez, M.D., co-investigator Targeting Protease Activated Receptor 1 to Promote Myelin Repair NMSS, RG4958A5/1 4/1/2015-3/31/2018
Louis (Jim) J. Maher, III, Ph.D., Sang-Hyn Oh, Ph.D., principal investigators; Moses Rodriguez, M.D., co-investigator Novel Oligonucleotides to Regenerate Myelin in Multiple Sclerosis Minnesota Partnership for Biotechnology and Medical Genomics 1/16/2016-1/15/2018
Moses Rodriguez, M.D., principal investigator A Recombinant Human Monoclonal Antibody for Promotion of Myelin Repair in Multiple Sclerosis Hilton Foundation 1/1/2008-12/31/2016
Moses Rodriguez, M.D., co-investigator Genetic-Epigenetic Determinants of Recovery from Demyelinating Attacks in Humans: A Study of the MHC Region European Regional Development Fund FNUSA-ICRC .1.05/1.1.00/02.0123 1/2011-12/31/2015
Moses Rodriguez, M.D., principal investigator Regenerative Human Antibodies for the Treatment of Hypoxia-Mediated Periventricular Leukomalacia Acorda 22-NH-Rod-1 11/1/2014-11/3/2015
Chella S. David, Ph.D., principal investigator; Moses Rodriguez, M.D., co-investigator Role of HLA Class II Genes in Demyelination National Institutes of Health, NS52173 9/2/2010-7/31/2015; 4/1/2006-3/31/2010
Moses Rodriguez, M.D., principal investigator Good Manufacturing Practices to Treat MS & Human Demyelinating Diseases Mayo Discovery and Innovation Award 12/1/2011-12/31/2014
Moses Rodriguez, M.D., co-investigator Elucidating the Role of Radial Glial Progenitors in Neonatal and Pediatric White Matter Disease T. Denny Sanford Pediatric Collaborative Research Fund 6/1/2012-5/31/2014
Moses Rodriguez, M.D., co-principal investigator, and Sang-Hyun Oh, Ph.D., co-principal investigator Nanopore Biosensor for Kinetics of Reparative Antibodies on Plasma Membranes National Institutes of Health, R01- GM092993 6/1/2010-5/31/2014
Moses Rodriguez, M.D., co-investigator Treatment of Periventricular Leukomalacia with Recombinant, Central Nervous System-Specific Human Monoclonal Antibodies CTSA Scholarly Opportunity Award 1/1/2013-12/31/2013
Moses Rodriguez, M.D., principal investigator Novel Treatment of a Mouse ALS Model Using Neuron-Protective Monoclonal Antibodies Mayo Small Grants Program 11/1/2012-12/31/2013
Moses Rodriguez, M.D., co-investigator DNA Aptamers to induce remyelination in multiple sclerosis National Institutes of Health Relief NS78622-01 1/1/2012-12/31/2013
Shailendra Giri, principal investigator; Moses Rodriguez, M.D., co-investigator Commensal Gut-Derived Anaerobes as Novel Therapy for Inflammatory Autoimmune Diseases Department of Defense, W81XWH-10-1-0254 9/1/2010-8/31/2013
Moses Rodriguez, M.D., principal investigator Natural Autoantibody-Mediated Microcontact Printing Novel Methodology Development Award 8/1/2012-7/31/2013
Moses Rodriguez, M.D., principal investigator Collaborative Mayo Grant on the Mechanisms of Injury in Multiple Sclerosis National Multiple Sclerosis Society Collaborative Research Center Grant 4/2004-4/2013
Moses Rodriguez, M.D., principal investigator Clinical Translation of a Neuron-Protective Recombinant Human Antibody National Institutes of Health, R21 NS073684 4/1/2011-3/31/2013
Marc C. Patterson, M.D., principal investigator; Moses Rodriguez, M.D., co-investigator Mayo Pediatric MS Center of Excellence National Multiple Sclerosis Society 1/2010-3/2013
Moses Rodriguez, M.D., and Sang-Hyun Oh, Ph.D., co-principal investigators Microfluidic Neurotechnology for Neuronal Survival and Regeneration Minnesota Partnership for Biotechnology and Medical Genomics No. 08-10 2/1/2011-1/31/2013
Moses Rodriguez, M.D., principal investigator Treatment of Viral Infections with Inhibitory Viral RNA-Dependent RNA-Polymerase Virus HIPFA Discovery/Translation Award 1/1/2010-12/31/2012
Moses Rodriguez, M.D., principal investigator Preclinical Studies of an Antibody to Promote Remyelination Applebaum MS Research Grant 1/1/2007-12/30/2012
Moses Rodriguez, M.D., principal investigator IND Submission of Antibody 22 for Remyelination for MS Hilton Fund for Multiple Sclerosis 10/1/2008-9/30/2012
Ashutosh Mangalam, principal investigator; Moses Rodriguez, M.D., co-investigator Therapeutic Efficacy of Metformin in the Disease Process of EAE National Institutes of Health, R21 NS065928 5/1/2010-3/31/2012
Allan J. Bieber, Ph.D., principal investigator; Moses Rodriguez, M.D., co-investigator Genetic Analysis of Spontaneous Remyelination National Institutes of Health, R01- NS048357 4/1/2008-3/31/2012
Istvan Pirko, principal investigator; Moses Rodriguez, M.D., collaborator Role of CD8+ T Cells in the Formation of T1 Black Holes in Animal Model of MS National Institutes of Health, NS 58698 4/1/2008-3/31/2012
Moses Rodriguez, M.D., and Sang-Hyun Oh, Ph.D., co-principal investigators High-Resolution Nano-LAMP Microarrays to Measure the Binding Strength of Therapeutic Human Natural Auto-Antibodies on Target Cell-Surface Antigens Minnesota Partnership for Biotechnology and Medical Genomics No. 08-10 1/1/2009-12/31/2011
Orhun H. Kantarci, M.D., principal investigator; Moses Rodriguez, M.D., co-investigator Non-Ambulatory Impairment in Benign Multiple Sclerosis National Multiple Sclerosis Society 1/2007-12/2010
Roberto Cattaneo, Ph.D., principal investigator; Moses Rodriguez, M.D., co-investigator Measles Viruses With Added Vaccines National Institutes of Health, R01-A157761 4/1/2006-3/31/2010
Nancy Kuntz, principal investigator; Moses Rodriguez, M.D., co-investigator Mayo Pediatric MS Center of Excellence National Multiple Sclerosis Society 1/2006-12/2009
Moses Rodriguez, M.D., principal investigator Mechanism of Axonal Loss in Multiple Sclerosis Donald and Frances Herdrich Foundation 11/2004-11/2009
Dean M. Wingerchuk, M.D., principal investigator; Moses Rodriguez, M.D., co-investigator Aspirin for the Treatment of MS-Related Fatigue National Multiple Sclerosis Society, RG 3808-A1 10/2006-10/2009
Moses Rodriguez, M.D., principal investigator Remyelination in Multiple Sclerosis: Neural Precursor- Based Repair Canadian Multiple Sclerosis Society 7/2005-6/2008
Jeffrey R. Basford, M.D., Ph.D., principal investigator; Moses Rodriguez, M.D., co-investigator Mayo Rehabilitation Research Training Center National Institutes of Health, HD07447 3/1/2003-2/28/2008
Moses Rodriguez, M.D., principal investigator Effect of Statins on Central Nervous System Remyelination National Multiple Sclerosis Society PP 1391 3/2007-2/2008
Moses Rodriguez, M.D., principal investigator A Recombinant Human Monoclonal Antibody for Promoting Myelin Repair in Multiple Sclerosis Conrad Hilton Foundation 11/2004-11/2007
Moses Rodriguez, M.D., principal investigator Mayo MSTP M.D./Ph.D. Program National Institutes of Health, T32GM65841-01 7/2003-7/2007
Allan J. Bieber, Ph.D., principal investigator; Moses Rodriguez, M.D., co-investigator Genetic Analyses of Spontaneous Remyelination National Multiple Sclerosis Society 10/2003-9/2005
Allan J. Bieber, Ph.D., principal investigator with Acorda Pharmaceuticals Human Monoclonal Antibodies for CNS Remyelination Phase II STTR grant from National Institutes of Health 9/2002-9/2005
Moses Rodriguez, M.D., principal investigator, Project 4 under the supervision of Jack Antel Remyelination in Multiple Sclerosis: Neural Precursor-Based Repair MS Research Foundation of Canada 10/2001-10/2004
Moses Rodriguez, M.D., principal investigator Human Monoclonal Antibodies for CNS Remyelination National Institutes of Health, R41 NS40172-01 12/1/2000-11/30/2002
Moses Rodriguez, M.D., co-investigator with Timothy Neuberger from Acorda Therapeutics Human Antibodies to Promote CNS Regeneration National Institutes of Health, R43 NS40209-01 12/1/2000-11/30/2002