Current and Past Graduate / Postdoc Students

  • Fernado Reyers, Houston, TX (September 1987 - May 1988). Molecular cloning of phenylalanine hydroxylase gene to knock out the gene in mouse embryonic stem cells.
  • Fernado Reyers, Summer undergraduate student, Houston, TX (June 1989 - September 1989). Molecular cloning of alpha 1-antitrypsin gene to knock out the gene in mouse embryonic stem cells.
  • David Teeple, SURF student, University of Arizona, Tucson, AZ (May - August 1997). Expression of mutated cystic fibrosis transmembrane conductance regulator protein in baby hamster kidney cells.
  • Jey-Hsin Chen, Rotation student of M.D. and Ph.D. program, Mayo Clinic College of Medicine, Rochester MN. (October - November 1997).Molecular cloning of cystic fibrosis transmembrane conductance regulator gene. He is a resident in Boston.
  • Vivek Mittal, SURF student, Boston University, Boston, MA (May - August 1998). Expression of mutated multidrug resistance-associated protein in baby hamster kidney cells. He is a graduate student in the University of Washington.
  • Paul M. Magtibay, M.D. resident rotation, Mayo Clinic Scottsdale, Scottsdale, AZ (March-July 1998). Cell culture (of multidrug-resistant cells). He is a surgeon.
  • Dominic Jezierski, SURF student, University of Arizona, Tucson, AZ (May - August 1999). Purification of multidrug resistance-associated protein.
  • Kevin Wu, SURF student, University of Southern California CA (July - August, 2002). Insertion of an epitope (HA epitope) into an extra-cellular loop of cystic fibrosis transmembrane conductance regulator. He is a medical school student.
  • Aaron Goldberg, UBRP student, University of Arizona, Tucson, AZ (May - August 2003). Insertion of the mutated multidrug resistance associated protein into baccular virus expression system. He is an undergraduate student.
  • Jenny Ahn, SURF student, Massachusetts Institute of Technology, Cambridge MA (June - August, 2003). Make mutations in the nucleotide binding domains of multidrug resistance associated protein. She is an undergraduate student.
  • Doriane Trompier, Graduate student of the Institut de Biologie et Chimie des Proteines, Lyon, France. (February - April, 2001). The project was flavonoids binding to the multidrug resistance protein MRP1 and reversion of multidrug resistance caused by over-expression of MRP1. The research article “Multiple flavonoid-binding sites within multidrug resistance protein MRP1” is published in CMLS Cellular and Molecular Life Sciences 60, p2164-2177.
  • Doriane Trompier, Graduate student of the Institut de Biologie et Chimie des Proteines, Lyon, France. (February - April, 2002). The project was molecular mechanism of the hypersensitivity to the multidrug resistance modulator verapamil in the MRP1-overexpressing cells. The research article “Verapamil and its derivative trigger apoptosis through glutathione extrusion by multidrug resistance protein MRP1” has been submitted to Cancer Research. Doriane Trompier is a postdoctoral fellow in Dr. Chimini’s laboratory in France.
  • Zhenhua Huang, Graduate student of the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. (October, 2000 - June, 2004). The project is floppase activity of the purified multidrug resistance protein MRP1. The research article “Flourescent modified phosphatidylcholine floppase activity of reconstituted multidrug resistance-associated protein MRP1” has been accepted by Biochemica et Biophysica Acta. Zhenhua Huang has received his Ph.D. degree.
  • Runying Yang, Postdoctoral fellow (October, 2001 - May, 2009). Mechanism of ATP-dependent anti-cancer drug transport by multidrug resistance associated protein. The article “ATP binding to the first nucleotide binding domain of MRP1 plays a regulatory role at low nucleotide concentration whereas ATP hydrolysis at the second plays a dominant role in ATP dependent LTC4 transport” has been published in J. Biological Chemistry.
  • Qing Zhao, Postdoctoral fellow (June, 2003 - October, 2006). The mechanism of ATP induced conformational change of multidrug resistance associated protein. She is a research associate now.