Grants and Patents

Active grants

  • Title: TRIM5alpha-Mediated Block of HIV-1 Production
    Role: Principal investigator
    Funded by: National Institute of Allergy and Infectious Diseases
    Major goal: Elucidate the mechanism of TRIM5alpha-mediated block of HIV-1 production
    Duration: September 2008 to August 2011
  • Title: Small Animal Model for XMRV Infection
    Role: Principal investigator
    Funded by: National Institute of Allergy and Infectious Diseases
    Duration: February 2011 to January 2013
  • Title: Novel Tissue Engineering of Patient-Specific Islet Cells for Diabetes Therapy
    Role: Co-principal investigator (with Jonathan Slack, Ph.D., University of Minnesota)
    Funded by: Minnesota Partnership for Biotechnology and Medical Genomics
    Duration: February 2011 to January 2013
  • Title: Regulated Long-Term B-Type Natriuretic Peptide Delivery in Hypertensive Heart Disease
    Role: Co-principal investigator (with Alessandro Cataliotti, M.D., Ph.D.)
    Funded by: National Heart, Lung, and Blood Institute
    Duration: July 2010 to June 2015

Completed grants

  • Title: Self-Regulating HIV Vectors for Hemophilia A Gene Therapy
    Role: Principal investigator
    Funded by: National Hemophilia Foundation
    Major goal: Establish HIV vectors that can regulate their own transgene expression in vivo
    Duration: July 2006 to June 2009
  • Title: Toward a Gene Therapy for Cocaine Addiction
    Role: Co-investigator (with Stephen Brimijoin, Ph.D.)
    Funded by: Minnesota Partnership for Biotechnology and Medical Genomics
    Duration: May 2006 to April 2008
  • Title: Detection of a Novel Human Retrovirus in Prostate Cancer Patients
    Role: Principal investigator
    Funded by: Mayo Clinic Prostate Cancer SPORE Career Development Award
    Major goal: Conduct an epidemiological survey of XMRV infection in prostate cancer patients
    Duration: October 2007 to September 2008
  • Title: Activation of Pluripotent Switch for Autologous Derivation of Renewable Stem Cells
    Role: Principal investigator
    Funded by: Marriott Award in Individualized Medicine Disease Risk and Regenerative Medicine Initiative
    Major goal: Establish a genomic modification-free iPS generation strategy
    Duration: November 2008 to October 2010
  • Title: iPS Technology for a Renewable Source of Pancreatic Beta Cells
    Role: Principal investigator
    Funded by: Bernard and Edith Waterman Awards in Individualized Medicine
    Major goal: Generate iPS cells from type 1 diabetes patients and differentiate them into insulin-producing cells
    Duration: July 2009 to June 2010
  • Title: iPS Technology for a Renewable Source of Pancreatic Beta Cells
    Role: Principal investigator
    Funded by: Eisenberg Stem Cell Trust
    Major goal: Generate iPS cells from type 1 diabetes patients and differentiate them into insulin-producing cells
    Duration: January 2010 to June 2011

Patents

  • Name: Stable HIV Vector Production
    Holders:
    Yasuhiro Ikeda, Yasuhiro Takeuchi, Francisco Martin, Kyri Mitrophanous and Mary K. Collins
    Number: U.K. patent GB0220467A
  • Name: Retroviral Vector and Stable Packaging Cell Lines
    Holders: Yasuhiro Ikeda, Yasuhiro Takeuchi, Francisco Martin, Kyri Mitrophanous and Mary K. Collins
    Numbers: World Intellectual Property Organization WO2004022761; U.S. patent 20060258006
  • Name: Materials and Methods for Improved Vaccination
    Holders: Yasuhiro Ikeda, Michael Palmowski, Lucien Lopes, Mary K. Collins and Vincenzo Cerundolo
    Numbers: World Intellectual Property Organization WO2004110485; U.S. patent 20060257416
  • Name: Induced Pluripotent Stem Cells
    Holders: Yasuhiro Ikeda, Andre Terzic, Satsuki Yamada, Alumdena Perez-Fernandez, Amber Mael and Timothy Nelson
    Number: Provisional U.S. patent filed (WO 2010/017562)