Grants

Active grants

  • Title: Cytokine Modulation of Amyloid-Beta-Associated Pathologies in Amyloid Precursor Protein Mouse Models of Alzheimer's Disease
    Objective: To understand the role of inflammatory mechanisms on Alzheimer's disease-associated pathologies
    Role: Principal investigator
    Funded by: National Institute on Aging
    Grant number: R01AG32991-01A2J
    Duration: 03/01/2011 to 02/29/2015
  • Title: Cytokine Modulation of Amyloid-Beta-Associated Pathologies in Amyloid Precursor Protein Mouse Models of Alzheimer's Disease
    Objective: To understand the role of inflammatory mechanisms on microglial activation and amyloid-beta deposition
    Role: Principal investigator
    Funded by: American Health Assistance Foundation
    Grant number: A2009061
    Duration: 04/01/2009 to 03/31/2012

Completed grants

  • Title: Amyloid-Beta and Beyond: γ-Secretase as a Drug Target for Central Nervous System Disease
    Objective: To understand the potential of γ-secretase inhibition for the treatment of central nervous system diseases
    Role: Co-principal investigator
    Funded by: National Institutes of Health
    Grant number: P01AG025531
    Duration: 01/01/2006 to 01/30/2011
  • Title: Effect of γ-Secretase Inhibition on the Anti-Amyloid-Beta Immune Responses
    Objective: To understand inflammatory mechanisms following amyloid-beta vaccinations
    Role: Principal investigator
    Funded by: Alzheimer's Association
    Grant number: NIRG-05-13909
    Duration: 09/01/2005 to 08/31/2007
  • Title: Immune-Mediated Mechanisms Underlying Central Nervous System Amyloid-Beta Clearance
    Objective: To understand potential mechanisms of amyloid-beta clearance following amyloid-beta vaccinations
    Role: Co-investigator
    Funded by: National Institute on Aging
    Grant number: R01AG018454
    Duration: 09/30/2003 to 06/30/2007
  • Title: In Situ Therapeutic Anti-Amyloid-Beta Delivery by Adenoviral Vectors
    Objective: To investigate the use of anti-amyloid-beta scFv as a potential therapy for Alzheimer's disease
    Role: Co-investigator
    Funded by: National Institute on Aging
    Grant number: R01AG21875
    Duration: 09/01/2002 to 08/31/2006