Location

Rochester, Minnesota

Contact

Sun.Zhifu@mayo.edu

Summary

Using bioinformatics and epidemiological approaches, Zhifu Sun, M.D., is exploring how cancer develops and what contributes to varied clinical outcomes in patients.

Dr. Sun mostly studies lung, breast and prostate cancers.

Focus areas

  • Lung cancer etiology and outcome research. Genetic susceptibility to lung cancer, molecular diagnostic and prognostic makers for lung cancer using gene expression microarray, genome-wide association studies, and next-generation sequencing (mRNA-seq and exome-seq).
  • Breast cancer genomics. Integrated next-generation sequencing data analysis of multiple genomic features (gene expression, methylation, copy number, single nucleotide variants) for their association with patient outcomes.
  • Epigenomics. Translational epigenomics research for biomarker identification, mainly DNA methylation and microRNA markers.
  • Algorithms and data processing. Algorithm and data preprocessing pipeline development for methylation and miRNA sequencing.

Significance to patient care

The identification of genetic or genomic markers will help to diagnose a disease early and potentially prevent its development. A deep understanding of a tumor's genetic makeup will also help treat patients differently for optimal outcomes.

Recent Publications

See my publications

Professional Details

Primary Appointment

  1. Health Sciences Research

Academic Rank

  1. Assistant Professor of Epidemiology
  2. Assistant Professor of Medical Informatics

Education

  1. MS - Heath Informatics University of Minnesota Medical School
  2. Resident - Anatomic Pathology Shandong Provincial Qianfoshan Hospital, China
  3. MS - Pathology Hebei Medical University, China
  4. Resident - Anatomic Pathology Shandong Provincial Qianfoshan Hospital, China
  5. MD College of Medicine, Qingdao University
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BIO-00028041

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