Location

Rochester, Minnesota

Contact

Schrum.Adam@mayo.edu

Summary

The laboratory is interested in how the immune system decides whether to destroy or tolerate tissues bearing persistent antigens. We first focus on the T cell antigen receptor, and how its structure, multi-subunit composition, and biochemical functions operate throughout the course of immune responses. We then study how the many other proteins and pathways involved in T cell signaling cooperate to compose a network with emergent properties to determine immune fate. Using cellular, molecular, biochemical, and proteomic techniques, we examine these processes in T cell responses to tumors and transplanted tissues.

Recent Publications

See my publications

Professional Details

Primary Appointment

  1. Immunology

Academic Rank

  1. Assistant Professor of Immunology

Education

  1. Postdoctoral Fellowship University of Basel, University-Hospital
  2. Ph.D. - Immunology University of Pennsylvania School of Medicine
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BIO-00095885

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