Location
Rochester, Minnesota
Summary
Dr. Sarkaria's laboratory research is focused on developing novel radiosensitizing strategies for the treatment of glioblastoma. Studies in the Sarkaria laboratory demonstrated that concurrent treatment with rapamycin can significantly enhance the efficacy of radiation therapy, and these studies have led to the development of a clinical trial that will evaluate this combination in newly diagnosed patient with GBM. Other studies in the laboratory are focused on understanding the potential benefit of EGFR inhibitors in combination with radiation therapy and evaluating mechanisms of sensitivity and resistance to temozolomide when combined with radiation. Dr. Sarkaria also is interested in imaging drug induced changes in tumor proliferation as a method for rapidly identifying those patients who are benefiting from a particular novel therapeutic strategy.
Recent Publications
See my publications
Professional Details
Primary Appointment
- Radiation Oncology
Academic Rank
- Professor of Radiation Oncology
Education
- BS - Biology and Chemistry University of California, Irvine
- MD University of California, Los Angeles
- Internship - Transitional University of Hawaii
- Residency - Radiation Oncology University of Wisconsin, Madison
- Research Fellowship - Radiotherapy Research Unit Institute of Cancer Research
- Post Doctoral Research Department of Oncology