Location

Rochester, Minnesota

Contact

Kumar.Shaji@mayo.edu Clinical Profile

Summary

My laboratory focuses on development of novel drugs for treatment of myeloma. We evaluate the in vitro activity of novel drugs, which are likely to have activity in the setting of myeloma, based on their mechanisms of action. Promising drugs are brought into the clinic through early stage clinical trials (Phase I/II studies). Additionally we evaluate novel combinations of different drugs to identify synergistic combination which can result in better treatment responses and eventually better patient outcome. The work on drug development is complemented by an active program studying the disease biology. The focus is on the study of bone marrow microenvironment in multiple myeloma and how it influences the tumor cells, especially the increased bone marrow microvessels seen in myeloma. A better understanding of the disease biology allows identification of valid therapeutic targets and in turn development of novel drugs.

Recent Publications

See my publications

Professional Details

Primary Appointment

  1. Hematology

Academic Rank

  1. Professor of Medicine

Education

  1. Research Associate - Mayo Foundation Scholar(Multiple Myeloma) DFCI/Harvard Cancer Center
  2. Fellow - Hematology/ Oncology Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  3. Clinical Residency - Internal Medicine Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  4. Senior Resident - Medical Oncology Institute Rotary Cancer Hospital, All-India Institute of Medical Sciences
  5. Clinical Residency - Internal Medicine All-India Institute of Medical Sciences
  6. Internship - Rotatory Internship All-India Institute of Medical Sciences
  7. MB BS All-India Institute of Medical Sciences
  8. Pre-Medical Union Christian College
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BIO-00027411

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