Primary research interests have been in the development of new immunosuppressive drug regimens in solid organ transplantation. This has involved Phase 1-4 trials of newly developed immunosuppressive drugs both at a local and a national level. Current trials involve multiple Mayo sites. In addition, I have a long standing interest in renal disease in non renal solid organ transplant, particularly liver transplant. This has involved patients from the pre transplant phase to long term followup including hepatorenal syndrome, post transplant renal failure and ESRD in liver transplant recipients.