Rochester, Minnesota


gastineau.dennis@mayo.edu Clinical Profile


Dennis A. Gastineau, M.D., established the Human Cellular Therapy Laboratory in the Division of Transfusion Medicine at Mayo Clinic's campus in Rochester, Minnesota, for the purpose of translating cell-based novel therapies into products appropriate for administration to patients.

Dr. Gastineau has established a sister laboratory at Mayo Clinic's campus in Phoenix/Scottsdale, Arizona, to enable multisite trials of novel therapies and bring new treatments to the Southwest.

Focus areas

  • Immunotherapy and cancer vaccines
  • Immunomodulation, involving treatment of inflammatory bowel disease complications, graft-versus-host disease and induction of immune tolerance
  • Translational assistance to investigators, assuring that processes comply with the Current Good Manufacturing Practices (CGMP) of the Food and Drug Administration (FDA)

Significance to patient care

The Human Cellular Therapy Laboratory was the first contract manufacturer for Dendreon Corp., bringing the first FDA-approved cellular immunotherapy for prostate cancer to market.

The laboratory has held or participated in more than 20 investigational new drug trials designed to treat neurodegenerative diseases, renal disease, inflammatory bowel disease, graft-versus-host disease, lymphoma, glioblastoma and ovarian cancer.

The laboratory endeavors to partner in bringing first-in-human treatments to Mayo Clinic's patients.

Professional highlights

  • President, Foundation for the Accreditation of Cellular Therapy, the accrediting body for cellular therapy and bone marrow transplant programs, 2016-2018


See my publications


Primary Appointment

  1. Laboratory Medicine and Pathology

Administrative Appointment

  1. Hematology

Academic Rank

  1. Associate Professor of Medicine


  1. Fellow - Hematology - research Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  2. Fellow - Hematology - clinical Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  3. Resident - Internal Medicine University of Iowa Hospitals and Clinics
  4. Internship University of Iowa Hospitals and Clinics
  5. MD Mayo Medical School, Mayo Clinic College of Medicine
  6. BA - Economics Carleton College

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