Rochester, Minnesota


Faubion.William@mayo.edu Clinical Profile


The research interest of William A. Faubion, M.D., is the pathophysiology and novel therapeutics of Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease (IBD). In collaboration with patients seen in the IBD clinic, Dr. Faubion's team utilizes discovery platforms (omic technologies) to develop hypotheses about disease mechanisms to test in the laboratory using cell lines or animal systems. This team of scientists and generous patients has built a collection of clinical data linked to biological samples in which to explore individualized approaches to therapy.

Focus areas

  • Epigenetics of T cell-fate decisions leading to intestinal inflammation
  • T regulatory cell biology in intestinal inflammation
  • Cell therapy of IBD
  • Clinical trial conduct and design
  • Systems biology approach to IBD

Significance to patient care

IBD is a heterogeneous disease with a precise molecular fingerprint. Dr. Faubion's team works to identify and classify patients with a unique molecular identity to improve prognosis and precision therapy. The team's work on cell therapy in fistulizing disease has already led to breakthroughs in therapy for this highly morbid condition.


See my publications


Primary Appointment

  1. Consultant, Division of Gastroenterology and Hepatology, Department of Internal Medicine

Joint Appointment

  1. Consultant, Division of Pediatric Gastroenterology and Hepatology, Department of Pediatric and Adolescent Medicine
  2. Consultant, Department of Immunology

Academic Rank

  1. Professor of Medicine
  2. Professor of Pediatrics
  3. Professor of Immunology


  1. Mayo Clinic Scholar - Laboratory of Dr. Cox Terhorst Beth Israel Deaconess Medical Center, Harvard Medical School
  2. Fellow - Pediatric and Adult Gastroenterology Mayo Clinic in Rochester
  3. Fellow - Gastrointestinal Fellow, Laboratory of Gregory J. Gores, MD Center for Basic Research in Digestive Diseases, Mayo Clinic Rochester Centers
  4. Resident - Internal Medicine/Pediatrics Texas Medical Center, University of Texas, Houston
  5. MD University of Texas Health Science Center, Medical School, University of Texas, Houston
  6. BA Dartmouth College

Mayo Clinic Footer