Application Information — Pilot and Feasibility Grants

Call for 2014 Pilot and Feasibility Program letters of intent

The Mayo Clinic Metabolomics Resource Core requests proposals for funding during the 2014 grant year. These awards are intended to support projects that will provide preliminary data for new, extramural grant submissions. The review criteria will emphasize innovation and the potential of the project, if successful, to have a significant impact on an important research problem. Funds will be available for four to six awards with up to $50,000 in direct costs for each award. The duration of the awards will be 12 months.


Applications are due no later than March 15, 2014.


  • All basic, translational or clinical investigators located at institutions within the United States who are eligible to apply as a principal investigator (PI) for NIH grants may submit applications.
  • Early-stage investigators and investigators who are new to the field of metabolomics are especially encouraged to apply.
  • Investigators who have extensive use of metabolomic technology in their research program are generally ineligible for funding.


  • Up to $50,000 in direct costs for each award
  • Eligible expenses include costs for data acquisition and analysis offered through the Mayo Clinic Metabolomics Resource Core
  • Investigator effort will not be supported
  • Protocol duration of one year
  • NIH application guidelines will be followed

For additional Pilot and Feasibility funding opportunities, please visit the other RCMRCs:

Review procedure

Content experts will form the review panel. Recommendations for funding will be forwarded to the national RCMRC Executive Committee, who will make final approvals for funding. Applications will be scored using the current NIH Scoring System.

Review criteria will include the following:

  • Alignment with goals of program
  • Scientific merit and innovation
  • Likelihood to support novel research questions that leverage the skills of the Mayo Clinic Metabolomics Resource Core
  • Likelihood of future extramural funding
  • Feasibility within time and budget proposed
  • Qualifications and scientific environment of the investigators
  • Priority will be given to projects that have samples ready for analysis

Application information

Applications are due no later than March 15, 2014. Earliest anticipated start date is June, 2014.

Applications must include the following components and use PHS 398 continuation format page unless otherwise specified in the invitation to submit an application. Please provide the following:

  1. Cover letter. Include project title, principal investigator, co-investigators and affiliations.
  2. Abstract. Provide a one-paragraph summary of the project.
  3. Layperson summary. Include a two- to three-sentence summary that can be understood by a lay audience.
  4. Specific aims. Include a one-page outline of your project goals.
  5. Research plan. Provide background, hypothesis, prior work summary, experimental plan, timeline and extramural funding. Also include a justification for the use of the Mayo Clinic Metabolomics Resource Core services and resources. Include isotopes to be utilized, sample handling requirements and opportunities for future intellectual property/commercialization as appropriate (five-page limit).
  6. References. List any references cited.
  7. Biographical sketches. For each PI and co-investigator, please use the PHS 398 biographical sketch format.
  8. Resource inventory. List the resources that will be made available for the project.
  9. Budget and justification. Include a budget (limit of $50,000 direct per application) and justification. Please use the PHS 398 Detailed Budget for Initial Budget Period format page.

Please bundle all application documents into a single PDF file. Submit the file via email to, and indicate "Mayo Clinic Metabolomics Resource Core Application" in the subject line.

To discuss whether your needs can be met in the proposed timeframe, please contact:

Reporting and tracking of impact

Progress reports will be required at the end of the funding period and yearly for two years after the end of the funding period. Information tracked will include the following:

  • Grants applied for and funded
  • Publications
  • Impact on career development
  • Impact on clinical practice
  • Invention disclosures or other commercialization activities resulting

As mandated by the NIH Common Fund, all metabolomics data and associated metadata will be publicly deposited in the Metabolomics Data Repository managed by Data Repository and Coordination Center (DRCC).


If you have questions about grants or the application process, please contact:

Michael J. Joyner, M.D.

Michael D. Jensen, M.D.


NIH Public Access Policy requires that all publication that results from NIH funding be uploaded to PubMed Central. Review the process for uploading publications.

Awardees must cite the Mayo Clinic Metabolomics Resource Core grant as a funding source in any resulting publications. Use this language:

This publication was made possible by Mayo Clinic Metabolomics Resource Core through grant number U24DK100469 from the National Institute of Diabetes and Digestive and Kidney Diseases and originates from the National Institutes of Health Director's Common Fund.