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Rochester, Minn.
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Treatment Trial of Droxidopa and Pyridostigmine to Improve Orthostatic Hypotension Without Aggravating Supine Hypertension
Location:
Rochester, Minn.
Trial status:
Open for Enrollment
Why is this study being done?
The hypothesis is that pyridostigmine will improve the safety factor of ganglionic neural transmission, while Droxidopa will replete the postganglionic neuron of norepinephrine (NE). This combination should result in enhanced orthostatic release of NE. The investigators have already demonstrated that pyridostigmine does not raise supine blood pressure.
NCT ID:
NCT01370512
IRB Number:
10-008810
Who can I contact for additional information about this study?
Rochester: Tonette Gehrking 507-284-0336