Examination of the Pancreas in New-onset Diabetes (EXPAND Study)


Rochester, Minn.

Trial status:

Open for Enrollment

Why is this study being done?

Compared to the general population, subjects >50 years of age with new-onset diabetes (DM) are 8-times more likely to have pancreatic cancer (PaC). The likelihood of PaC in new-onset DM is further increased in those who have weight loss or elevated CA19-9. In this study patients with newly diagnosed diabetes will be prospectively identified. Those with weight loss and/or elevated pancreatic cancer marker (CA 19-9) will undergo pancreatic imaging. All subjects will be followed up to 24 months. If successful in identifying surgically removable PaC, this study will fundamentally change our practice and will be a major breakthrough in PaC treament and research.

Who is eligible to participate?

Patient Characteristics: --Suspected or definite new-onset diabetes based on recent blood sugar and hemoglobin A1c values - No acute illness or steroid therapy - No prior pancreas surgery

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