Electronic Surveillance Sniffer for Early Detection and Intervention for Acute Kidney Injury: PRAISE Trial

Location:

Rochester, Minn.

Trial status:

Open for Enrollment

Why is this study being done?

A prospective controlled, unblinded clinical trial will be conducted among AKI patients who are detected by the use of AKI sniffer. The investigators will randomize consecutive patients who were detected to have AKI by AKI sniffer into two groups. In one group (control group), patients will receive standard clinical care by the primary ICU physicians. The primary physicians who take care of the control subjects will be kept blinded of the results of the AKI sniffer. All the ICU physicians will receive a copy of KDIGO (March 2012) guidelines for management of AKI prior to the initiation of the patient accrual. In the intervention group, the research team will inform the primary care team about the occurrence of the AKI and provides a copy of KDIGO guidelines for management of AKI to the clinicians. Each subject will be followed until hospital discharge or for a maximum of 3 months, for clinical and laboratory data including peak serum creatinine, creatinine at the end of follow up, peak AKIN stage, along with other secondary outcomes. The investigators will exclude the prevalent cases (AKI patients who have had AKI documented in their medical records by clinicians prior to the ICU admission).

Who is eligible to participate?

Inclusion Criteria: - All patients who are admitted in adult ICUs in Mayo Clinic Rochester - Foley catheter for hourly UOP measurement Exclusion Criteria: - Prisoners - Patients less than 18 years old. - Lack of research authorization (in control group) - ESRD on dialysis or s/p kidney transplantation - Known AKI before admission to ICU - Moribund patients - Prevalent AKI admission in ICU (patients who have diagnosis of AKI documented in their medical records prior to ICU admission)

Last updated:

3/28/2014

NCT ID:

NCT01621152

IRB Number:

11-000007