P.R.O.G.R.E.S.S.: PSC Resource Of Genetic Risk, Environment and Synergy Studies.


Rochester, Minn.

Trial status:

Open for Enrollment

Why is this study being done?

Primary Sclerosing Cholangitis (PSC) is a progressive liver disorder of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PSC. This study is being done to investigate whether genes make people more likely to develop PSC. Discovery of these genes will help us to better understand how PSC developes and subsequently, to apply new approaches for its prevention, diagnosis and treatment.

Who is eligible to participate?

Inclusion Criteria: - Men, Women, and Children between the ages of 5-90 with a history of PSC. - PSC patients who have had a liver transplant are eligible. - Family members (1st degree relatives) of enrolled PSC patients are eligible. Exclusion Criteria: - Individuals with no history of PSC or those unable to provide consent.

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