A Children s Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens

Location:

Rochester, Minn.

Trial status:

Open for Enrollment

Why is this study being done?

OBJECTIVES: - Establish a mechanism to bank specimens of tumor cells and host germline DNA from patients with acute lymphoblastic leukemia (ALL) or non-Hodgkin lymphoma at first and subsequent relapse. - Make these specimens available to qualified researchers to study the biology of ALL. OUTLINE: This is a multicenter study. Patients undergo collection of bone marrow and peripheral blood at diagnosis of relapse and/or at the end of the first month of treatment. Patients are followed periodically for up to 10 years. PROJECTED ACCRUAL: Not specified.

Who is eligible to participate?

DISEASE CHARACTERISTICS: - Diagnosis of acute lymphoblastic leukemia (ALL) or prior history of non-Hodgkin lymphoma - In first or subsequent marrow relapse with ≥ 25% blasts in bone marrow and/or peripheral blood - Bone marrow and/or peripheral blood samples (≥ 5 mL) required at the time of diagnosis of relapse PATIENT CHARACTERISTICS: - Not specified PRIOR CONCURRENT THERAPY: - No concurrent systemic antileukemic treatment administered for current relapse - Intrathecal chemotherapy allowed - On-therapy relapse allowed

Last updated:

8/5/2014

NCT ID:

NCT00897325

IRB Number:

07-007836