A Study Of MR Elastography Of The Breast

Overview

About this study

The purpose of this study is to establish the test-retest repeatability of an enhanced, fast free-breathing breast MR Elastography technique and compare it against the standard MRE acquisition.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Ability to provide informed consent.

  • At study onset, female subjects will be between 18 and 75 years of age, without known breast cancer. Willing and able to undergo a non-contrast breast MRI/MRE exam and a breast ultrasound shear wave elastography (SWE) exam during a separate study visit. For subjects of childbearing potential, willingness to complete a urine pregnancy test prior to initiation of MRI procedures.

Exclusion Criteria: 

  • Prior or existing presentation of breast cancer.

  • Women who are or may be pregnant or lactating. Pregnancy status will be assessed with a urine pregnancy test administered prior to the MRI exam. No additional urine sample will be obtained for the elastography portion of the study.

  • Subjects with breast implants will be excluded.

  • For Magnetic Resonance Imaging (MRI) participants:

    • Absolute contraindications to MRI including pacemaker, AICD device, cochlear implant, VP shunt, aneurysm clip, deep brain stimulator, or severe claustrophobia.

    • Body weight over 500 pounds (or 226 kilograms), and chest/waist/hip circumference over 160 cm, due to MRI system limit (70-cm bore, <400 lbs).

 

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 02/10/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Arvin Forghanian-Arani, Ph.D.

Contact us for the latest status

Contact information:

Kathy Brown

(507) 538-8274

brown.kathy@mayo.edu

More information

Publications

Publications are currently not available