A Study Of Patient-Reported Outcome Instrument For Glucocorticoid Withdrawal Syndrome

Overview

About this study

The purpose of this study is to develop and psychometrically validate a patient-reported outcome (PRO) instrument to measure the severity and impact of glucocorticoid withdrawal syndrome (GWS) during the early postoperative period following curative treatment of endogenous hypercortisolism.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥18, CS/MACS, curative surgery with remission planned/confirmed, postoperative GC replacement

Exclusion Criteria:

  • Persistent/recurrent hypercortisolism in weeks 1–12; major postoperative complications that prevent survey completion, inability to self-report

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 03/02/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Irina Bancos, M.D., M.S.

Open for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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