Ultrasound Visualization Of The Hamstring Neurovascular Pedicle: Establishing A Surgical Landmark For Selective Neurectomy

Overview

About this study

The purpose of this study is the evaluation of ultrasound imaging to detect a neurovascular pedicle crossing the sciatic nerve in the posterior thigh of healthy adults and patients with spastic hamstring muscles undergoing neurectomy. Determine the feasibility of ultrasound detection of the neurovascular pedicle in the hamstring region by measuring the proportion of subjects (healthy adults and preoperative patients) in whom the pedicle is visualized on ultrasound (present/absent) compared to intraoperative.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria (Healthy Volunteers): 

  • Adults (≥18 years); BMI <25; no history of thigh or sciatic nerve surgery; able to consent.

Inclusion Criteria (Patients):

  • Adults indicated for hamstring motor branch neurectomy for spasticity; BMI <25; no prior thigh surgery; able to consent; scheduled for surgery at Mayo Clinic.

Exclusion Criteria:

  • BMI ≥25; prior surgery or trauma to posterior thigh; pregnancy (if applicable); any contraindication to ultrasound (none expected). Vulnerable populations (children, prisoners, etc.) are not targeted.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 11/6/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Kitty Wu, M.D.

Contact us for the latest status

Contact information:

Kitty Wu

wu.kitty@mayo.edu

More information

Publications

Publications are currently not available