A Study Of Photon-counting Detector CT With Improved Spectral Resolution
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 25-011963
About this study
The purpose of this study is to determine the changes in multi-energy CT image quality of a PCD-CT scanner with improved spectral resolution relative to the existing commercial PCD-CT scanner. We hypothesize that the innovation PCD-CT scanner with improved spectral resolution will yield multi-energy CT images with increased contrast-to-noise ratio, lower image noise, more accurate material quantification, or decreased artifacts relative to multi-energy CT images acquired using the current commercial detector and that radiologists will prefer images from the innovation PCD-CT scanner. Multi-energy CT images for a range of body regions and clinical applications will be evaluated.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
Adult patients 18 to 99 years of age
Patients receiving a clinically indicated PCD-CT exam for one of the relevant body regions/clinical applications.
Patients who are able and willing to sign the informed consent.
Exclusion Criteria:
Minors less than 18 years old
Patient unable to provide written informed consent
For subjects who would require iodinated contrast material, a previous reaction to iodinated contrast media or an eGFR below 30 mL/min/1.73m2
Pregnancy
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 01/14/2026. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Cynthia McCollough, Ph.D. |
Contact us for the latest status |
|
More information
Publications
Publications are currently not available