A Study Of CFD And Other Vascular Biomechanics Of The Cerebrovascular System
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Jacksonville, Florida: 25-004522
About this study
The purpose of this study is to evaluate how advanced vascular biomechanics (e.g., CFD, PWV) correlate with neurovascular disease progression and patient outcomes. Determine whether advanced imaging techniques (e.g., phase-contrast MRI/4D Flow, vessel wall imaging, 7T MRI) improve the accuracy and precision of CFD modeling in patients with cerebrovascular pathologies. Assess the feasibility of using biomechanics data (including velocity, pressure and wall shear stress) to guide and potentially optimize endovascular or surgical planning.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
Exclusion Criteria:
Non adult patients
Inability to complete MRI (e.g., certain pacemakers, metallic implants, or severe claustrophobia which requires sedation) for prospective arm.
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 6/05/2025. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Jacksonville, Fla.
Mayo Clinic principal investigator Rabih Tawk, M.D. |
Open for enrollment |
|
More information
Publications
Publications are currently not available