Inclusion Criteria:

• Subject is ≥18 years of age
• Subject with:
  • EITHER
    an arterial blood sample ordered as part of their standard medical care; examples include:
    • An individual without chronic liver disease who is undergoing arterial blood sampling as part of their standard of care in the outpatient arena (e.g., for evaluation of acid-base abnormalities or pulmonary disease)
    • An individual with chronic liver disease who is undergoing arterial blood sampling as part of their standard of care in the outpatient arena (e.g., as part of a liver transplantation work-up)
  • OR
    an indwelling arterial catheter (e.g., suitable for obtaining an arterial blood sample); examples include:
    • An individual undergoing surgery in which an arterial catheter is placed as part of their standard of care
    • An individual in the intensive care unit in which an arterial catheter is placed as part of their standard of care
• Subject is able to provide a venous blood sample at the time of their arterial blood sample collection; examples of venous blood locations sampled include:
  • Peripheral (via standard phlebotomy from an upper extremity vein)
  • Central (via a peripherally inserted central catheter (PICC) or via central venous catheter (CVC))
• Subject is able to provide two capillary blood samples (via two finger pricks) at the time of their arterial blood sample collection
• Subject (or their designated medical decision maker) provides informed consent for participation in this study

Exclusion Criteria:

• Subject is a member of a vulnerable group, including individuals who may be vulnerable to coercion or undue influence, such as prisoners
• Subject has a condition that, in the opinion of one of the Study Team members, produces unusual health risk to the subject by their participation

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 06/19/2024. Questions regarding updates should be directed to the study team contact.