Bronchoscopy Combining Stimulated Raman Histology With Artificial Intelligence for Rapid Lung Cancer Detection

Overview

About this study

The purpose of this study is to develop and validate a deep learning algorithm to assist physicians in the detection of cancer in bronchoscopic forceps biopsies (TBBx) of peripheral lung nodules/masses based on images acquired with the NIO Laser Imaging System from fresh/unprocessed tissue specimens.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria: 

  • The patient or legal guardian is willing and able to understand, sign and date the Ethics committee approved study specific Informed Consent Form.
  • The patient is 22 years of age or older.
  • The patient is scheduled for routinely indicated staging of the mediastinum (EBUS-TBNA) and planned peripheral lung biopsy procedure (peripheral-TBBx/TBNA) with an intermediate to high pretest probability of lung cancer based on clinician suspicion.
  • The patient can tolerate the clinical procedure as indicated.

Exclusion Criteria: 

  • Patient is a prisoner.
  • The participant, in the judgment of the Investigator, may be inappropriate for the intended study procedures.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 2/05/2025. Questions regarding updates should be directed to the study team contact.
 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Bryan Husta, M.D.

Contact us for the latest status

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

More information

Publications

Publications are currently not available