Real-time Lung Physiology in Fighter Pilots

Overview

About this study

The purpose of this study is to determine the ability to accurately track changes in lung physiology in a closed loop ventilator system with various environmental and airway/lung challenges.  Lung physiology will be altered using challenges that impact airway tone, increase thoracic loads, alter lung compliance or intrathoracic fluid and increase susceptibility to atelectasis. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Healthy adults with no history of cardiac or respiratory related disease (no asthma).
  • Nonsmoker.
  • Similar demographics with USAF pilots – age ranges (20 to 50 years).
  • BMI < 32 kg/m^2 – generally ovoid significant obesity although some variation in body habitus is good.
  • Regularly active – no exercise limitations – orthopedic or other.

Exclusion Criteria:

  • Age under 20 or over 50 years.
  • Smoker.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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