Gastrointestinal Lewy Bodies: A Cause or Effect of Parkinson’s Disease?

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Jacksonville, Florida: 15-005408
    Sponsor Protocol Number: 15-005408

About this study

The purpose of this proposal is to explore whether the presence of Lewy pathology in the gastrointestinal tract is associated with functional disturbances such as constipation and dysphagia in both Parkinson’s disease patients and non-Parkinson’s disease patients, and if present in the latter patients whether this relates to the subsequent development of Parkinson’s disease.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:   

  • Age 18 years or older
  • Able to provide informed consent
  • Resident of the United States (to make it possible to conduct future subject follow-up using the National Death Index)
  • Undergoing colonoscopy and/or esophagogastroscopy and/or surgery as part of routine clinical investigation

Exclusion Criteria:

  • Patients not undergoing colonoscopy and/or esophagogastroscopy and/or surgery as part of routine clinical investigation
  • Patients with bleeding disorder

 

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Kenneth DeVault, M.D.

Open for enrollment

Contact information:

Kenneth Devault M.D.

(904)953-6970

devault.kenneth@mayo.edu

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CLS-20359591

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