Diagnostic Ultrasound in the Evaluation of Athletes with Vocal Cord Dysfunction

Overview

  • Study type

    Interventional
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 15-008428
    • Minneapolis, Minnesota: 15-008428
    Sponsor Protocol Number: 15-008428

About this study

The purpose of this study is to find out if we can use ultrasound to identify people with breathing problems from their vocal cords. Ultrasound machines use sound waves to see inside your body. In this case, we will be looking at the vocal cords in your neck. If we can use ultrasound to see this problem, then we won’t need to use a camera inside of a person’s throat to diagnose this problem.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Females or males between 18 and 45 years of age
    • Two of whom have been diagnosed with VCD based upon prior video laryngoscopy
    • The other two of whom do not have known VCD or symptoms of VCD including:
      • Excessive dyspnea
      • Wheezing
      • Stridor
      • Exercise intolerance
  • Must be willing and able to participate in a submaximal ramp protocol exercise test on a stationary bike.

Exclusion Criteria: 

  • Allergy to ultrasound gel
  • Current neck infection
  • Open skin lesion over the anterior neck 
  • Inability to access the skin of the anterior neck (e.g, large beard, neck flexor muscle spasm, etc)
  • Laryngeal mass or tumor
  • Prior laryngeal surgery
  • Any condition that precludes the ability to perform a vigorous exercise test on a stationary bicycle (e.g., musculoskeletal pain, neurologic condition, peripheral vascular disease)
  • Pregnancy  
  • History of a cardiac condition or cardiac surgery, more than one risk factor for coronary artery disease, or symptoms suggestive of a cardiac condition including palpitations, chest pain, or dizziness or loss of consciousness with exercise.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jonathan Finnoff, D.O.

Closed for enrollment

Contact information:

Jonathan Finnoff D.O.

(612)313-0526

Finnoff.Jonathan@mayo.edu

Minneapolis, Minn.

Mayo Clinic principal investigator

Jonathan Finnoff, D.O.

Closed for enrollment

Contact information:

Jonathan Finnoff D.O.

(507)266-5566

Finnoff.Jonathan@mayo.edu