Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.
The population studied will be for the unrelated case and control analyses, subjects between the ages of 18 and 100 who meet the IHS diagnostic criteria for migraine and who are willing to answer a brief screening diagnostic questionnaire and to donate 40 cc of blood or 5 ml of saliva for DNA processing
For the sampling of family pedigrees for the Whole Exome sequencing based studies the age range will be 10 to 100 to allow the enrollment of willing younger relatives of the affected proband subject.
In addition to subjects recruited from the patients, trainees and staff at the Mayo Clinic Rochester campus and from offsite visits with events in the community and on college campuses, subjects will be recruited from the Mayo Clinic Migraine research website.
Controls will be non-affected age and gender matched individuals unrelated to case subjects who do not meet diagnostic criteria for migraine or migrainous headaches.