Stress Management and Resiliency Training (SMART) Integrated Into Treatment of Major Depression

Overview

  • Study type

    Interventional
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Austin, Minnesota: 16-007944
    • Rochester, Minnesota: 16-007944
    NCT ID: NCT03275961
    Sponsor Protocol Number: 16-007944

About this study

The investigators are doing this research study to find out if the Stress Management and Resiliency Training (SMART) therapy will help subjects with their major depression treatment.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Attending the Mayo Clinic Depression Center and Behavioral Health Clinic at Mayo Clinic Health System, Austin, Minnesota
  • DSM-V diagnostic confirmation of major depressive disorder (MDD)
  • Baseline PHQ-9 scores in the range of ≥6-≤19, and HAMD-17 score 8-18, or QIDS-C16 score of 6-20
  • Able to speak English
  • Participants will continue taking any prescribed medications from their clinical treatment team
  • Patients with co-morbid secondary diagnoses of persistent depressive disorder and generalized anxiety disorders will be included in the study.

Exclusion Criteria:

  • Participants with bipolar disorder
  • Active psychosis
  • Active suicidal ideations
  • Active substance abuse meeting criteria for substance use disorders except nicotine
  • Obsessive compulsive disorder
  • Active Panic disorder with agoraphobia, other phobic disorder
  • Active Posttraumatic stress disorder
  • Active Severe personality disorders.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Austin, Minn.

Mayo Clinic principal investigator

Ashok Seshadri, M.D.

Closed for enrollment

Contact information:

Jose Rico CCRP

(507)293-5268

Rico.Jose@mayo.edu

Rochester, Minn.

Mayo Clinic principal investigator

Ashok Seshadri, M.D.

Open for enrollment

Contact information:

Ashok Seshadri M.D.

(507)433-7351

Seshadri.Ashok@mayo.edu

.
CLS-20308940

Mayo Clinic Footer