A Study of Clinical Evaluation of a PET/MR System

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 15-001909
    Sponsor Protocol Number: 15-001909

About this study

The first objective of this pilot research protocol is to evaluate the quality of PET from the SIGNA PET/MR system and to compare the quantitative accuracy of PET images from the PET/MR system to PET images from a standard PET/CT system. The second objective of this pilot research protocol is to compare the image quality from MRI images acquired on the SIGNA PET/MR to clinical MR images acquired on a standard 3.0T MRI system.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • PET Cohort:
    • Patients 18 to 100 years of age
    • Patients who are scheduled for a clinically indicated F-18 FDG or Ga-68 DOTATATE PET/CT study
    • Patients who are able and willing to sign the informed consent will be enrolled
    • Patients who have a BMI of at least 18.5 kg/m²
    • Patients who pass standard clinical MRI screening procedures
  • MRI Cohort:
    • Patients 18 to 100 years of age
    • Patients who are able and willing to sign the informed consent will be enrolled
    • Patients who pass standard clinical MRI screening procedures
    • Patients who have had a clinical MRI scan performed within 7 days of the PET/MRI scan

Excluison Criteria:

  • PET Cohort
    • Patients who are unable to lay quietly for an additional 60 minutes of imaging
    • Patients who are claustrophobic
    • Patients who weigh more than 350 lbs or whose body habitus precludes them from participation
  • MRI Cohort:
    • Patients who are unable to lay quietly for an additional 60 minutes of imaging
    • Patients who are claustrophobic
    • Patients who weigh more than 350 lbs or whose body habitus precludes them from participation

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Bradley Kemp, Ph.D.

Open for enrollment

Contact information:

Terry Brinkman

(507)284-4377

tbrinkman@mayo.edu