Breast Cancer: Can We Predict Pathological Complete Response following Neoadjuvant Treatment?

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Scottsdale/Phoenix, Arizona: 14-006021
    Sponsor Protocol Number: 14-006021

About this study

This project will investigate whether ctDNA analysis in newly diagnosed stage I, II, III breast cancer patients treated with neoadjuvant systemic therapy can predict pathological Complete Response (pCR).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Patients eligible for a neoadjuvant approach with either endocrine therapy or chemotherapy:
  • Age >18years old
  • Co-morbidities allow for the treatment of breast cancer with surgery and systemic therapy
  • Stage I, II, or III breast cancer with a minimum tumor size of at least T1c
  • Patient believed to be surgically resectable at completion of neoadjuvant therapy
  • No clinical evidence of metastatic disease

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Barbara Pockaj, M.D.

Open for enrollment

Contact information:

Regina Becker

(480)342-6079

Becker.Regina@mayo.edu

.
CLS-20308371

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