Uric Acid Levels and Endothelial Functions

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 05-004191
    NCT ID: NCT02862522
    Sponsor Protocol Number: 05-004191

About this study

Uric acid is a risk factor for coronary artery disease (CED) in postmenopausal women but the association with inflammation and coronary microvascular endothelial dysfunction is not well-defined. The aim of this study was to determine the relationship of serum uric acid, inflammatory markers and CED.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Referred to Mayo Clinic for cardiac catheterization 
  • Postmenopausal

Exclusion Criteria:

  • History of percutaneous coronary intervention
  • Coronary artery bypass graft surgery 
  • Unstable angina pectoris 
  • Valvular heart disease 
  • Peripheral vascular disease 
  • Known congestive heart failure

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Amir Lerman, M.D.

Contact us for the latest status

Contact information:

Monica Olson

(507)255-2649

Olson.Monica2@mayo.edu

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CLS-20307892

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