Analysis of Immunostaining during Mohs Micrographic Surgery to Improve Detection of Negative Surgical Margins in Patients with Squamous Cell Carcinoma and Chronic Lymphocytic Leukemia (CLL)/ Non-Hodgkins Lymphoma (NHL)

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-003948
    Sponsor Protocol Number: 16-003948

About this study

The goal of this study is to evaluate the use of immunostains during Mohs micrographic surgery (MMS) will improve detection of negative surgical margins in patients with cutaneous squamous cell carcinoma (cSCC) and chronic lymphocytic leukemia (CLL)/non-Hodgkin lymphoma (NHL). The study will also aim to evaluate the use of immunostains during MMS to improve the outcomes (local recurrence, metastasis, and disease-specific death) in patients with cSCC and CLL/NHL.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Adults (> 18 years of age)
  • Existing diagnosis of CLL/NHL
  • New diagnosis of cutaneous squamous cell carcinoma

Exclusion Criteria: 

  • Existing diagnosis of recurrent or metastatic cutaneous squamous cell carcinoma
  • Existing diagnosis of underlying genodermatosis with associated increased risk of cutaneous squamous cell carcinoma (e.g.xeroderma pigmentosum

 

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Christian Baum, M.D.

Open for enrollment

Contact information:

Julie Gecox

(507)266-0464

Gecox.Julie@mayo.edu

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CLS-20306553

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