Knee Range of Motion during Activities of Daily Living

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-005083
    Sponsor Protocol Number: 06-005083

About this study

The study aim is to quantify knee joint range of motion during activities of daily living. Four groups will be studied: adults with knee osteoarthritis, adults with postoperative knee arthrofibrosis, adults who have had a total knee arthroplasty, and a control group of adults with no lower extremity joint disease. Results from this study will define the level of which current joint replacements provide sufficient range of motion relative to a healthy control group.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

Control group:

  • 40-80 years of age
  • No pain that limits normal range of motion in all lower extremity joints
  • No previous arthroplasty or surgery on the lower extremities

Arthrofibrosis group:

  • 40-80 years of age
  • Primary total knee arthroplasty with a resurfaced patella, cemented, modular, metal-backed, all-poly, and posterior-stabilized within the past 3 years and at least 1 year post-op due to knee osteoarthritis
  • Knee arthrofibrosis resulting in a range of motion < 90 degrees on the total involved knee with range of motion > 90 degrees on the contralateral knee
  • No pain that limits normal range of motion in ipsilateral ankle & knee and contralateral ankle, knee and hip
  • No previous lower extremity arthroplasty or realignment procedures beside the total involved knee

Osteoarthritis group:

  • 40-80 years of age
  • Primary unilateral knee osteoarthritis KL Grade 3 or 4 with KL grade ≤ 1 on the contralateral knee
  • No pain that limits normal range of motion in ipsilateral ankle & knee and contralateral ankle, knee and hip
  • No previous arthroplasty or realignment procedures of the lower extremity

Total Knee Arthroplasty group:

  • 40-80 years of age
  • Primary total knee arthroplasty with a resurfaced patella, cemented, modular, metal-backed, all-poly, and posterior-stabilized within the past 3 years and at least 1 year post-op due to knee osteoarthritis
  • No pain that limits normal range of motion in ipsilateral ankle & knee and contralateral ankle, knee and hip
  • No previous lower extremity arthroplasty or realignment procedures beside the total involved knee

Exclusion Criteria: 

Control group:

  • Diagnosis of musculoskeletal or neurological pathology or disorder

Osteoarthritis group:

  • Diagnosis of musculoskeletal or neurological pathology or disorder in other lower extremity joints

Arthrofibrosis Group:

  • Diagnosis of musculoskeletal or neurological pathology or disorder in other lower extremity joints

Total knee arthroplasty group:

  • Diagnosis of infectious, inflammatory, neurologic, or post-traumatic arthritis

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Matthew Abdel, M.D.

Closed for enrollment

Contact information:

Christine Huyber

(507)266-0984

Huyber.Christine@mayo.edu