A Study of Carotid MRI/MRA to Evaluate the Amount of Plaque in the Arteries of Patients Taking Cholesterol Lowering Medication

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-004060
    Sponsor Protocol Number: 16-004060

About this study

The purpose of this study is to assess if it is possible to use a carotid MRI/MRA to see if cholesterol lowering medication is causing a reduction in the amount of plaque in the arteries.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Adults starting PCSK9 inhibitors for treatment of hypercholesterolemia
  • Able to come back to Mayo for follow-up imaging at 3-9 months and 12-18 months following initiation of therapy

Exclusion Criteria  

  • Pregnant or nursing
  • Are not on PCSK9 inhibitors 
  • Has renal failure
  • GFR < 30   
  • Has claustrophobia
  • Has gadolinium allergy

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

John Huston, M.D.

Open for enrollment

Contact information:

Suson Walsh CCRP

(507)293-0039

Walsh.Suson@mayo.edu