A Study to Collect and Maintain Clinical Grade Genetic Sequencing from the Bone Marrow of Patients with Multiple Myeloma or Related Plasma Cell Malignancies

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Scottsdale/Phoenix, Arizona: 16-003428
    • Jacksonville, Florida: 16-003428
    • Rochester, Minnesota: 16-003428
    NCT ID: NCT02884102
    Sponsor Protocol Number: MMRF-002

About this study

The purpose of this study is to profile and keep genetic sequencing from the bone marrow of patients who have multiple myeloma or another plasma cell malignancy. This will allow the comparing of genetic analysis with corresponding clinical information, for the purpose of identifying and applying disease biomarkers, for personalized treatments.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Must have a diagnosis of multiple myeloma or related malignancy 
  • Will have standard of care bone marrow aspirates 
  • Male or female from any race or ethnicity
  • Must be at least 18 years of age at the time of registration
  • Procedure-specific signed informed consent form prior to initiation of any study-related procedures

Exclusion Criteria

  • Is not fit enough to undergo a bone marrow aspirate, (enrolling study physician's discretion to decide)
  • Incarcerated 
  • Pregnant 
  • Has had another malignancy within the last five (5) years (except for basal or squamous cell carcinoma, or in situ cancer of the cervix) where there is a possibility to contaminate the bone marrow aspirate

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Leif Bergsagel, M.D.

Open for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

855-776-0015

Jacksonville, Fla.

Mayo Clinic principal investigator

Leif Bergsagel, M.D.

Open for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

855-776-0015

Rochester, Minn.

Mayo Clinic principal investigator

Leif Bergsagel, M.D.

Open for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

855-776-0015

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

International patient clinical studies questions