Sleep Extension and Blood Pressure

Overview

  • Study type

    Interventional
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-000987
    NCT ID: NCT02929810
    Sponsor Protocol Number: 16-000987

About this study

Evidence suggests that roughly 30% of the US adult population sleeps less than 7 hours per night, and those who do show 20-52% increased risk to develop cardiovascular diseases, particularly hypertension. 

The purpose of this study is to look at the cardiovascular and metabolic effects of prolonged sleep in prehypertensive and stage 1 hypertensive people who report habitual short sleep.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Age: 18 to 65 (inclusive)
  • Gender: both males and females
  • Body mass index (BMI): 18.5-34.9 kg/m2
  • Habitual sleep duration: <7 hours
  • Presence of either:
    • Prehypertension: office systolic BP (SBP) 120-139 mmHg and/or diastolic BP (DBP) 80- 89 mmHg and awake ambulatory SBP/DBP averaging <135/85 mmHg59;
    • Stage 1 hypertension: office SBP 140-159 mmHg and/or DBP 90-99 mmHg and awake ambulatory SBP/DBP averaging ≥135/85mmHg59
  • Absence of any chronic medical conditions other than prehypertension or stage 1 hypertension, seasonal or environmental allergies
  • On no prescription medications other than oral contraceptive pills, or intrauterine devices.
  • Not pregnant or breast feeding and not intending to become pregnant or breast feed
  • Not a current smoker or tobacco user
  • Ability to provide written informed consent

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Virend Somers, M.D., Ph.D.

Open for enrollment

Contact information:

Trudy Hansen RPSGT

cplsleep@mayo.edu