A Study to Determine the Microbial Population of the Intestines in Patients with Active or Treated Inactive Eosinophilic Esophagitis

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-001097
    Sponsor Protocol Number: 16-001097

About this study

The purpose of this study is to collect stool samples and determine the intestine microbe environment in patients who have active or treated inactive eosinophilic esophagitis.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Clinical diagnosis of Eosinophilic Esophagitis
  • Age 18-65
  • Has clinically indicated endoscopy/ biopsies for Eosinophilic Esophagitis
  • Healthy volunteers of age and sex matched controls from a biobank

Exclusion Criteria

  • Prior history of abdominal surgeries (except appendectomy and cholecystectomy)
  • Known diagnosis of inflammatory bowel disease, microscopic colitis, celiac disease, atopic dermatitis, active asthma or other inflammatory conditions
  • Antibiotic use within the past 4 weeks (they can be enrolled after a four week washout period and subsequent use during the 6 month study duration does not exclude them)
  • Bowel preparation for colonoscopy within the past week
  • Vulnerable adults
  • Age ≥ 66

 

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

David Katzka, M.D.

Open for enrollment

Contact information:

Debra Geno CCRP

(507)538-0367

Geno.Debra@mayo.edu

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CLS-20228327

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