A Study of Environmental Effects on the Intestine Bacteria Commonly Present in Children and Adolescents with Multiple Sclerosis

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 14-001425
    Sponsor Protocol Number: 003

About this study

The purpose of this study is to better understand multiple sclerosis in children and adolescents, see how it is different from adult MS, and learn if genes, the environment, or both put them at increased risk of getting MS.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Children are eligible for this study as cases or controls if they are eligible for and enrolled in the Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis study

 

Exclusion Criteria

  • Patients are not eligible for study participation if
    • Antibiotics or probiotics have been used within 60 days prior to enrollment
    • Steroids have been used within 45 days prior to enrollment
    • Ongoing treatment includes any disease-modifying therapy other than glatiramer acetate or interferon
    • Disease-modifying therapy treatment agent has changed (including new agent or discontinuation) 90 days or less prior to enrollment
  • Children are not eligible to participate as pediatric controls if
    • They are 21 years of age or older
    • Antibiotic or probiotics have been used within 60 days prior to enrollment
    • Steroids have been used within 45 days prior to enrollment

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jan-Mendelt Tillema, M.D.

Closed for enrollment

Contact information:

Jaime Sorum

Sorum.Jaime@mayo.edu

.
CLS-20151851

Mayo Clinic Footer