A Study Relating Voice Characteristics and Coronary Artery Disease

Overview

  • Study type

    Interventional
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 14-000058
    Sponsor Protocol Number: 14-000058

About this study

The purpose of this study is to see if a new voice signal recording software program, called Beyond Clinical, can find a connection between abnormal voice signals and the presence and severity of coronary artery disease.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Subjects scheduled for cardiac catheterization (elective coronary angiogram for suspected myocardial ischemia and/or right heart study for suspected heart disease).
  • Matched control subjects who are age (+/- 2 years) and sex matched to the first 20 subjects of the cardiac cohort, and are scheduled to undergo a non-cardiac invasive procedure, such as hernia, varicose vein, dermatologic or ophthalmologic surgery
  • No-procedure control subjects who are age (+/- 2 years) and sex matched to the first 20 subjects of the cardiac cohort and are not scheduled to undergo any procedure for the duration of the study

Exclusions

  • Known history of coronary artery disease (documented by coronary angiography as greater than 50% obstruction)
  • Previous revascularization procedure (CABG or percutaneous balloon/stenting)
  • Known history of voice disorder either primary or secondary to neuromuscular or other pathology
  • Patients under the age of 18 years
  • Pregnancy

 

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Amir Lerman, M.D.

Open for enrollment

Contact information:

Danielle Jacobson

(507)255-7230

Jacobson.Danielle@mayo.edu

.
CLS-20151282

Mayo Clinic Footer