Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
- Rochester, Minnesota: 670-02
NCT ID: NCT01161953, NCT01161992
Sponsor Protocol Number: 670-02
About this study
Chronic cholestatic liver diseases, such as Primary Biliary Cirrhosis (PBC) and Primary Sclerosing Cholangitis (PSC), are progressive liver disorders of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PBC or PSC.
This study is being done to investigate whether genes make people more likely to develop PBC or PSC. Discovery of these genes will help us to understand better how PBC or PSC develops and subsequently, to apply new approaches for its prevention, diagnosis, and treatment.